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Dr Kate Best

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Senior Research Fellow

ORCID 0000-0002-4663-7141

Kate is a Senior Research Fellow working jointly in the Academic Unit for Ageing and Stroke Research and the Leeds Centre for Personalised Medicine and Health. She is currently working as part of the HDR-UK Better Care North Partnership to develop and evaluate an anticholinergic medication index to optimise prescribing among older people.

Kate is a statistician with an MSc in Medical Statistics from the University of Leicester (2010) and a PhD in Epidemiology from Newcastle University (2016). She has experience working with large routinely collected health data sets using a variety of different methods including survival analyses and multilevel modelling

Recent Funding Awarded

Pirmohamed M, Clegg A, Rodgers S, Alderson S, Alldred D, West R, Best KE, Walker L, Mehdizadeh D, Bonnet L, Buchan I, Farrin A, Foy R, Johnson O, Lawton T, McInerney C, Teale E, Young B. Development of a learning system to optimise anticholinergic medication prescribing for older people living with frailty. £1,200,000 (part of £3,400,000 HDRUK North award). 05/2020 to 03/2023

Rankin J, Best KE, O’Sullivan J. Length of stay (LOS) and predictors of LOS following paediatric congenital heart disease (CHD) repair in the North of England. £33,499. Newcastle upon Tyne Hospitals NHS Charity 2019-2020.

Rankin J Lingam R, Glinianaia S, Best KE. (2015). The prevalence and expected prevalence of selected childhood conditions in England; current figures and predictions. Newlife the Charity for Disabled Children. £14,999.

Recent Publications

Archer L, Relton S, Akbari A, Best K, Bucknall M, Conroy S, Hattle M, Hollinghurst J, Humphrey S, Lyons R, Richards S, Walters K, West R, van der Windt D, Riley R, Clegg A. Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. Age and Ageing 2024;52(3) https://doi.org/10.1093/ageing/afae057

Adesanya AM, Best KE, Coats L. Rankin J. Predictors of Post-Operative Hospital Length of Stay Following Complete Repair of Tetralogy of Fallot in a Pediatric Cohort in the North of England. Pediatric Cardiology 2024;45,92–99. https://doi.org/10.1007/s00246-023-03287-7

Best K, Todd O, Clegg A. Are frailty measurements derived using electronic health records fit for clinical use? Age and Ageing 2024;53(2):afae001. https://academic.oup.com/ageing/article/53/2/afae001/7595905

Alattas A, Nikolova S, Shuweihdi F, Best K, West R. The impact of long-term conditions on the progression of frailty. PLoS One 2023 18.4. https://doi.org/10.1371/journal.pone.0284011

Brown L, Heaven A, Quinn C, Goodwin V, Chew-Graham C, Mahmood F, Hallas S, Jacob I, Brundle C, Best K, Daffu-O’Reilly A, Spilsbury K, Young TA, Hawkins R, Hanratty B, Teale E, Clegg A. Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people. BMJ Open 2021;11(11):e048524. https://doi.org/10.1136/bmjopen-2020-048524

Rankin J. The improved prognosis of hypoplastic left heart: A population-based register study of 343 cases in England & Wales. Under review in Frontiers (congenital anomaly special edition), 2020.

Glinianaia SV, Morris J, Best KE, et al. Long-term survival of children born with congenital anomalies: a systematic review and meta-analysis of population-based studies. PLoS Medicine 2020, 17(9): e1003356.

Best KE, Rankin J, a EUROCAT working Group, Khoshnood B. Multilevel analyses of related public health indicators: The European Surveillance of Congenital Anomalies (EUROCAT) Public Health Indicators. Paediatric and Perinatal Epidemiology 2020, 34(2):122-129.

Slack E, Best KE, Rankin J, Heslehurst N. Maternal obesity classes, preterm and post-term birth: a retrospective analysis of 479,864 births in England. BMC Pregnancy and Childbirth 2019, 19: 434.

Best KE, Vieira R, Glinianaia SV, Rankin J. Socioeconomic inequalities in congenital heart disease mortality: a systematic review and meta-analysis. Paediatric and Perinatal Epidemiology 2019, 33(4).

Best KE, Seaton SE, Draper E, Field J, Kurinczuk J, Manktelow B, Smith LK. Assessing the deprivation gap in stillbirths and neonatal deaths by cause of death: a national population-based study. Archives of Disease in Childhood Fetal and Neonatal Edition 2019, 104: F624-630.

Best KE, Glinianaia SV, Morris J, Rankin J. Projected number of children with isolated spina bifida or Down syndrome in England and Wales by 2020. European Journal of Medical Genetics 2018, 61(9): 539-545.

Best KE, Tennant PWG, Rankin J. Survival, by birth weight and gestational age, in individuals with congenital heart disease: a population-based study. Journal of the American Heart Association: JAHA 2017, 6(7) e005213.

Basu A, Kirkpatrick E, Wright B, Pearse J, Best KE, Eyre J. The Tyneside Pegboard Test: development, validation, and observations in unilateral cerebral palsy. Developmental Medicine & Child Neurology 2017. doi: 10.1111/dmcn.13645.

Glinianaia SV, Best KE, Lingam R, Rankin J. Predicting the prevalence of cerebral palsy by severity level in children aged 3-15 years across England and Wales by 2020. Developmental Medicine & Child Neurology 2017, 59(8), 864-870.

Harbron R, Chapple C, O’Sullivan J, Best KE, Gonzalez A, Pearce M. Survival adjusted cancer risks attributable to radiation exposure from cardiac catheterizations in children. Heart 2016, 103(5), 341-346.

Best KE, Rankin J. Is advanced maternal age a risk factor for congenital heart disease? Birth Defects Research Part A 2016, 106 (6), 461-467.

Best KE, Rankin J. Survival of individuals with congenital heart disease: a systematic review and meta- analysis. JAHA: Journal of the American Heart Association 2016.

Best KE, Rankin J. Increased risk of congenital heart disease in twins in the North of England between 1998 and 2010. Heart 2015, 101 (22), 1807-1812.

Godse A, Best KE, Lawson A, Rosby L, Rankin J. Register based study of anorectal anomalies over 26 years: associated anomalies, prevalence and trends. Birth Defects Research Part A 2015, 103(7), 597-602.

McGivern M, Best KE, A EUROCAT Working Group, Rankin J. Epidemiology of congenital diaphragmatic hernia in Europe: a register-based study. Archives of Disease in Childhood, Fetal & Neonatal Edition 2014.

Best KE, A EUROCAT Working group, Rankin J. Hirschsprung’s disease prevalence in Europe: a register based study. Birth Defects Research Part A 2014, 100(9), 695-702.

Rankin J, Best KE. Disease-specific registers. Paediatrics and Child Health 2014, 24 (8), 337- 342.
Ghosh S, Best KE, Steel DW. Lens-iris diaphragm retropulsion syndrome during phacoemulsification in vitrectomized eyes. Journal of Cataract & Refractive Surgery 2013, 39(12), 1852-1858.

Brown M, Best KE, Pearce MS, Waugh J, Robson SC, Bell R. Long term cardiovascular risk in women with pre-eclampsia: systematic review and meta-analysis. European Journal of Epidemiology 2013, 28(1), 1-19

Best KE, Tennant PWG, Bell R, Rankin J. Impact of maternal body mass index on the antenatal detection of congenital anomalies. BJOG: An international journal of obstetrics and gynaecology 2012, 119(12), 1503-1511.

Best KE, Glinianaia SV, Bythell M, Rankin J. Hirschsprung’s disease in Northern England: a population-based study, 1990-2008. Birth Defects Research Part A 2012, 94(6), 477-80.

Best KE, Tenant PWG, Rankin J, EUROCAT working group. Epidemiology of small intestinal atresia in Europe: a register based study. Archives of Disease in Childhood, Fetal and Neonatal Edition 2012, 97(5), F353-F358.