Professor Andrew Clegg

Clegg A, Brown J, Wright J, McManus R, Rockwood K, Maximising independence for older people across community and hospital settings. NIHR Professorship £1,994,652.00; 01/12/2024-30/11/2029.

Abuzour AS, Clegg A, Garrett H, Best K, Alldred D, Pirmohamed M, Walker L, Rauf M. Designing and pilot testing an anticholinergic medication index clinical decision support system (ACMICS) for use in hospitals to support safer prescribing for older people at risk of medication-related harm. NIHR RfPB £256,241.00; 01/05/2025-30/04/2027.

Teale E, Crocker T, Hawkins R, Mossabir R, Best K, Clegg A, Kuruvilla R. Optimising transient ischaemic attack (TIA) pathways to reduce ethnicity-based Inequalities. NIHR HSDR £892,766.87; 01/04/2025-31/05/2028.

Clegg A, Hussain J, Best K, Brown L, Hawkins R, Marshall A, Murtagh F, Price D, West R, Kapadia D. The Wellbeing in Later Life in Bradford (WeLL-Bradford) Study. Nuffield Foundation £875,458.00; 01/10/2024-31/07/2028.

Bridges S, Wright J, Forster A, Clegg A, Birks Y, Wilberforce M, Samina K. NIHR Applied Research Collaborations Social Care Capacity Building. NIHR ARC £255,416; 01/04/2024-31/03/2026.

Forster A, Clegg A. Reimagining Ageing Doctoral Research Programme. The Dunhill Medical Trust £197,579.50

Sheppard J, Shanyinde M, Petrou S, Hobbs R, de Lusignan S, Allen J, Mant J, Ford G, Clegg A, Payne R, Ogden M, Williams M. Optimising Prescription of Treatment In older patients with Mild hypertension at Increased risk of Serious adverse Events (OPTIMISE2): a non-inferiority trial. NIHR HTA £2,368,309.26; 01/08/2022-30/04/2027.

Buchan I, Walker L, Clegg A, Mair F, Kullu C, Sperrin M, Relton S, van Staa T, Gabbay M, Ruddle R, Bollegala D, Maskell S, Shantsila E, Leeming G, Woodall A, Griffiths A. DynAIRx: AIs for dynamic prescribing optimisation and care integration in multimorbidity. NIHR Artificial Intelligence for Multiple Long-Term Conditions £2,807,430.00; 01/09/2022-31/08/2025.

Murtagh F, Pearson M, Walker L, Cohen J, Hussain J, Farrin A, Ziegler L, Clegg A, Spilsbury K, Collinson M, Cundill B, Fraser L, O’Cathain A, Taylor P, Johnson M, McAleese J, Rowson L. The Yorkshire & Humber Palliative Care Research Network: Addressing Inequalities Across All Ages. NIHR Cross-Programme £99,932.58; 01/02/2022-31/07/2023.

Goodwin V, Whitney J, Cockcroft E, Frost J, Crocker T, Hamilton F, Din S, Lamb S, Lyndon H, Hulme C, Clegg A, Creanor S, Sanders T. Digital and Remote Enhancements for the Assessment and Management of older people living with frailty (DREAM). NIHR Programme Development Grants £149,463; 01/01/2022-31/03/2023.

Brown L, Forster A, Clegg A, Williams A, Schofield P, Suleman A, Antcliff D, Grice A. Developing a self-management programme for pain in older people. NIHR HS&DR Programme £513,450.64; 01/04/2021-31/03/2025.

McManus R, Clegg A, Mant J, Payne R, Clarke C. Optimising structured medication reviews: A real-time observational cohort study with integrated qualitative evaluation (OSCAR). NIHR ARC East Midlands £461,508; 01/04/2021-30/09/2023.

Walters K, Clegg A, Goodman C, Marston L, Hopkins J, Cooper C, Logan P, Skelton D, Hunter R, Manthorpe J, Gardner B, Drennan V, Frost R, Avgerinou C. Clinical and cost-effectiveness of a personalised health promotion intervention enabling independence in older people with mild frailty (‘HomeHealth’): A Randomised Controlled Trial. NIHR HTA £1,833,313.78, 01/05/2020-30/04/2023

Clegg A, Crocker T, Ensor J, Forster A, Gladman J, Riley R. Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis NIHR HTA £298,981.99 01/12/2019-31/05/2021

Clegg A, Blagojevic-Bucknall M, Conroy S, Hulme C, Humphrey S, Nikolova S, Relton S, Richards S, Riha W, Riley R, van der Windt D, Walters K, West R. Development and evaluation of the electronic frailty index+ (eFI+) tool: integrated prognostic-decision modelling to target interventions for older people with moderate or severe frailty. NIHR HTA £548,507.12, 01/09/2019-30/04/2022.

Clegg A, Birks Y, Boijke C, Farrin A, Forster A, Hawkins R, Hawley M, Mountain G, Mukuria C, Rodriguez M, Reeve J, Richards S, Sheard L, Spilsbury K, Teale E, West R, Wilberforce M. Applied Research Collaborations: Older People with Frailty theme. NIHR Applied Research Collaborations £1,424,815; 01/10/2019-30/09/2024.

Ekers D, Coventry P, Dexter-Smith S, Brown D, Bosanquet K, Lovell K, Hill A, Clegg A, Traviss-Turner G, Gentry T. *M*ulti-morbidity in *O*lder Adults with *D*epression *S*tudy (MODS). NIHR PGfAR £2,429,219.00; 01/10/2018-01/07/2023 (69 months)

Walsh B, Fraser SDS, Roderick P, Clegg A, Barkham AM, Zhu S. The dynamics of frailty in older people: modelling impact on health care demand and outcomes to inform service planning and commissioning NIHR,HS&DR Programme £765,357.71; 01/02/2019-31/01/2022 (36 months)

Silman A, Clegg A, Prieto-Alhambra D, Strauss VY, Gentry T. Identifying trajectories of progression of frailty in elderly individuals. NIHR RfPB £149,550; 01/04/2019-31/03/2021.

Rodgers S, Hillcoat-Nalletamby S, Berridge D, Clegg A. Safe in my own home? Investigating the impact of community home modification services on hospital utilisation for fall injuries: a controlled longitudinal study using data linkage. Llywodraeth Cymru Welsh Government Health Research Grants. £222,376.00; 01/10/2017-30/09/2019.

Todd O, Young J, Clegg A. Optimising blood pressure management for older people with frailty. The Dunhill Medical Trust Research Training Fellowship £192,301, 2017 (36 months)

Clegg A, Young J, Bower P, Cundill B, Farrin A, Foster M, Foy R, Hartley S, Hawkins R, Hulme C, Humphrey S, Pendleton N, Teale E, West R, Holmes J. Personalised care planning to improve quality of life for older people with Frailty. NIHR, Programme Grants for Applied Research £2,754,006; 01/09/2017-31/12/ 2022 (64 months).

Clegg A, Young J, Forster A, Farrin A, Hartley S, Hulme C, Clarke D, Wright P, Cundill B. Randomised controlled trial evaluation to determine the clinical and cost effectiveness of a Home-based exercise intervention as Extended Rehabilitation in Older people with frailty following acute illness or injury, including internal pilot and embedded process evaluation (HERO). NIHR HTA £2,038,930.19; 01/03/2017- 31/05/2021 (51 months).

Young J, Clegg A, Nolan M, Mountain G, Teale E, Spilsbury K, Hanratty B, Noble B, Parry J Bates C, Hawkins R, Astell A, Young T. Primary Care-Based Management of Frailty in Older People. NIHR CLAHRC, £999,868; 01/01/2014-31/12/2018.

Clegg A, Young J. The Home-Based Older People’s Exercise (HOPE) Programme. An exercise programme to improve the functional status of community-dwelling frail older people. Royal College of Physicians & Dunhill Medical Trust Research Fellowship. £109,536, 01/10/09 – 31/09/2011.

Bellelli G, Brignoli O, Canevelli M, Cherubini A, Clegg A, Dubois B, Ferrara M, Cristina F, L Frisoni, GB, Grande G, Jessen F, Kennelly SP. Magni A, Marelli M, Marengoni A, Velilla NM, Shenkin SD, Suárez-Calvet M, Timmons S, Padovani A. Integrating frailty into decision-making for disease-modifying therapies in Alzheimer’s disease: a proposed expert-opinion based approach. The Journal of Prevention of Alzheimer’s Disease 2026 13(9):100666. https://doi.org/10.1016/j.tjpad.2026.100666

Chen T, Marino LV, Best K, Bhatnagar-Knox S, Humble V, Garnham M, Greenbank K, Relton S, Lim S, Clegg A. Extending eFall risk prediction to working-age adults within mental health and learning disability services: a clinical validation study. Scientific Reports 2026; https://doi.org/10.1038/s41598-026-51298-0

Brown L, Antcliff D, Clegg A, Grice A, Schofield P, Suleman A, Williams A, Harrison N, Kime N, Wright A, Lam N, Howdon D, Tebaldi D, Mossabir R, Hallas S, Crocker TF, Forster A. Developing the evidence and associated service models to improve pain management in older people living with frailty: a synopsis of the POPPY mixed method, co-design study. Health and Social Care Delivery Research 2026;14(18):1-42. https://doi.org/10.3310/gjlb4820

Van Royen FS, Wang A, Geersing G, Koshiaris C, Swain S, Banerjee A, Clegg A, Payne RA, Bellows BK, Hobbs FDR, McManus R, Sheppard JP. Association between antihypertensive treatment and hospitalisation or death due to falls according to sex, ethnicity, and social deprivation status: an observational cohort study in English primary care electronic health-care records. The Lancet Primary Care 2026. https://doi.org/10.1016/j.lanprc.2026.100150

Sheppard J, Bateman P, Wright-Drakesmith C, Clark CE, Barnes RK, Clegg AP, Ford GA, Gadhia S, Hinton W, Hobbs FDR, Jawad S, Khunti K, Lip GYH, de Lusignan S, Mant J, McCahon D, Meza-Torres B, Payne RA, Perera R, Reidy C, Seeley A, Seidu S, Tucker S, Van Der Veen R, Williams M, McManus R. Impact of structured medication reviews on prescribing in English Primary Care. British Journal of General Practice 2026; BJGP.2025.0617. https://doi.org/10.3399/BJGP.2025.0617

Reidy C, Seeley A, Tucker K, Agwunobi A, Bateman P, Clark CE, Clegg AP, Ford GA, Gadhia S, Hinton W, Hobbs FDR, Jawad S, Khunti K, Lip GYH, de Lusignan S, Mant J, McCahon D, Meza-Torres B, Rupert A. Payne RA, Perera R, Seidu S, Sheppard J, Williams M, Wright-Drakesmith C, McManus R, Barnes RK. Exploring the implementation and integration of structured medication reviews in primary care: A qualitative evaluation using normalization process theory. British Journal of General Practice 2026; BJGP.2025.0522. https://doi.org/10.3399/BJGP.2025.0522

Bray E, Hives L, Georgiou R, Benedetto V, Heyworth P, Doherty P, Williams NH, Rutter P, Spencer J, Clegg A, Caroline L Watkins. How feasible is self-monitoring for the management of prehypertension? The REVERSE study. BJGP Open 2026; BJGPO.2025.0231. https://doi.org/10.3399/BJGPO.2025.0231

Clegg A, Prescott M, Collinson M, Goodwin VA, Thompson E, Bestwick R, Bojke C, Clarke DJ, Day F, Forster A, Hall A, Hulme C, Peacock J, Ziegler F, Farrin AJ. Home-Based Extended Rehabilitation for Older People with Frailty (HERO): A Randomised Controlled Trial. Age and Ageing 2026; 55:afag011. https://doi.org/10.1093/ageing/afag011

Abuzour A, Wilson S, Woodall A, Mair F, Aslam A, Clegg A, Shantsila E, Gabbay M, Abaho M, Bollegala D, Cant H, Griffiths A, Hama L, Leeming G, Lo E, Maskell S, O’Connell M, Popoola O, Relton S, Ruddle R, Schofield P, Sperrin M, Van Staa T, Buchan I, Walker L. Developing an AI-Assisted Tool That Identifies Patients With Multimorbidity and Complex Polypharmacy to Improve the Process of Medication Reviews: Qualitative Interview and Focus Group Study. Journal of Medical Internet Research 2026;28:e74304. https://doi.org/10.2196/74304

Prescott M, Collinson M, Hall AJ, Bestwick R, Goodwin VA, Thompson E, Bojke C, Clarke DJ, Day F, Forster A, Hulme C, Peacock J, Ziegler F, Farrin AJ, Clegg A. Home-Based Extended Rehabilitation For Older People With Frailty (HERO): A Multicentre Randomised Controlled Trial with Health Economic Analysis and Process Evaluation. Health Technology Assessment, 2026;30(4):1-40. https://doi.org/10.3310/GJAC1602

Hall AJ, Ziegler F, Prescott M, Goodwin VA, Hulme C, Farrin AJ, Thompson E, Forster A, Clegg A, Clarke DJ. Process Evaluation Exploring Implementation and Delivery of a Home-Based Extended Exercise Intervention for Older People with Frailty: The HERO T

Heald AH, Lu W, R Williams, Mccay K, Clegg A, Todd C, Maharani A, Cook MJ, O’Neill TW. The influence of ethnicity on frailty in a United Kingdom (UK) population. The Journal of Frailty & Aging 2025; 14(6) https://doi.org/10.1016/j.tjfa.2025.100089

Agwunobi AJ, Seeley AE, Tucker KL, Bateman PA, Clark CE, Clegg A, Ford G, Gadhia S, HobbsFDR, Lip GYH, de LusignanS, Mant J,McCahon D, Payne RA, Perera R, Seidu S, Sheppard JP, Williams M, Wright-Drakesmith C, McManus RJ, Barnes RK. Understanding structured medication reviews delivered by clinical pharmacists in primary care in England: a national cross-sectional survey. BMJ Open 2025;15:e097012. http://doi.org/10.1136/bmjopen-2024-097012

Fujiwara T, Koshiaris C, Cai T, Wang A, Lee J, Lay-Flurrie S, Banerjee A, Clegg A, Payne RA, Swain S, Ogden M, Hoshide S, Kario K, Hobbs FDR, McManus RJ, Sheppard JP. Associations between falls and other serious adverse events and antihypertensive medication in individuals with dementia: An observational cohort study. PLOS Medicine 2025;22(9):e1004731 https://doi.org/10.1371/journal.pmed.1004731

Brundle C, Johansson JF, Best K, Clegg A, Forster A, Atkinson T, Foster M, Humphrey S, Iliff A, Inglis J, Walker C, Graham L. Development of methods to identify digitally excluded older people, and tailoring of interventions to meet their digital needs: a protocol for a mixed-methods study (the INCLUDE study). BMJ Open 2025;15(9):e102723. https://doi.org/10.1136/bmjopen-2025-102723

Asiimwe IG, Best K, Sofat R, Todd OM, Walker L, Jorgensen AL, Clegg A, Pirmohamed M. The anticholinergic medication index and dementia risk: evidence from the UK Biobank and All of Us research program, Age and Ageing 2025;54(11). afaf326, https://doi.org/10.1093/ageing/afaf326

Tadrous R, Forster A, Farrin A, Coventry PA, Clegg A. Exploring the perceptions of sedentary behaviour in community-dwelling older adults aged 75 and older: a series of focus group interviews. BMC Public Health 2025; 2558. https://doi.org/10.1186/s12889-025-23793-y

Hunter RM, Frost R, Kalwarowsky S, Marston L, Pan S, Avgerinou C, Clegg A, Cooper C, Drennan VM, Gardner B, Goodman C, Logan P, Skelton DA, Walters K. Funding Health Promotion Activities to Reduce Avoidable Hospital Admissions in Frail Older Adults (HomeHealth): Further Challenges to the “Cost-Effective but Unaffordable” Applied Health Economics and Health Policy 2025. https://doi.org/10.1007/s40258-025-00987-4

Hancox Z, Kingsbury SR, Conaghan PG, Clegg A, Relton SD. Primary care prediction of hip and knee replacement 1–5 years in advance using Temporal Graph-based Convolutional Neural Networks (TG-CNNs), Rheumatology 2025;64(8)4589–4598. https://doi.org/10.1093/rheumatology/keaf185

Crocker TF, Todd O, Clegg A. Around the EQUATOR With Clin-STAR: Systematic Reviews of Intervention Effectiveness; Challenges and Opportunities. Journal of American Geriatric Society 2025. https://doi.org/10.1111/jgs.19498

Nimmons D, Clegg A, Walters K. Using the new electronic frailty index (eFI2) to aid frailty identification and management in primary care. British Journal of General Practice 2025; 75 (755): 249-250. DOI: https://doi.org/10.3399/bjgp25X742473
Dent E, Clegg A, Roller-Wirnsberger R, Vetrano DL, Hoogendijk EO. Reorienting frailty in clinical practice, public health, and policy: the Lancet Commission on Frailty. The Lancet 2025. https://doi.org/10.1016/S0140-6736(25)01101-8

Wang A, Koshiaris C, Archer L, Riley RD, Snell KIE, Stevens R, Banerjee A, Usher-Smith JA, Swain S, Clegg A, Clark CE, Payne RA, Hobbs FDR, McManus RJ, Sheppard JP; STRATIFY investigators. Developing prediction models for electrolyte abnormalities in patients indicated for antihypertensive therapy: evidence-based treatment and monitoring recommendations. Journal of Hypertension 2025 https://doi.org/10.1097/hjh.0000000000004032

Devi R, Haunch KJ, Graham EH, Griffiths AW, Hodge G, Clegg A, Drummond M, Forster A, Pearce S, Spilsbury K, Thompson C. The uncertainties and questions of care home residents, relatives and staff as a basis for evidence-based improvement and research. Age and Ageing 2025;54(5). https://doi.org/10.1093/ageing/afaf125

Wightman H, Butterly E, Wei L, McChrystal R, Sattar N, Adler A, Phillippo D, Dias S, Welton N, Clegg A, Witham M, Rockwood K, McAllister DA, Hanlon P. Frailty in randomized controlled trials of glucose-lowering therapies for type 2 diabetes: An individual participant data meta-analysis of frailty prevalence, treatment efficacy, and adverse events. PLOS Medicine 2025. https://doi.org/10.1371/journal.pmed.1004553

Sinclair DR, Maharani A, Clegg A, Hanratty B, Tampubolon G, Todd C, Wittenberg R, O’Neill TW, Matthews FE. Differences in the risk of frailty based on care receipt, unmet care needs and socio-economic inequalities: A longitudinal analysis of the English Longitudinal Study of Ageing. The Journal of Frailty & Aging 2025;14(2). https://doi.org/10.1016/j.tjfa.2025.100012

Aslam A, Walker L, Abaho M, Cant H, O’Connell M, Abuzour AS, Hama L, Schofield P, Mair FS, Ruddle R, Popoola O, Sperrin M, Tsang JY, Shantsila E, Gabbay M, Clegg A, Woodall A, Buchan IE, Relton S. An Automation Framework for Clinical Codelist Development Validated with UK Data from Patients with Multiple Long-term Conditions. BMC Medical Research Methodology2025;25(138). https://doi.org/10.1186/s12874-025-02541-1

Tadrous R, Forster A, Farrin A, Coventry PA, Clegg A. 2025. Co-producing an intervention to reduce sedentary behaviour in community-dwelling older adults aged ≥ 75 informed by behaviour change theory. BMC Geriatrics 2025; 25(201). http://dx.doi.org/10.1186/s12877-025-05844-6

Witham MD, McDonald C, Wilson N, Rennie KJ, Bardgett M, Bradley P, Clegg AP, Connolly S, Hancock H, Hiu S, Nicholson K, Robertson L, Simms L, Steel AJ, Steves CJ, Storey B, Wason J, von Zglinicki T, Sayer AA. Metformin and physical performance in older people with probable sarcopenia and physical prefrailty or frailty in England (MET-PREVENT): a double-blind, randomised, placebo-controlled trial. The Lancet Healthy Longevity 2025;6(3). https://doi.org/10.1016/j.lanhl.2025.100695

England T, Walsh B, Brailsford S, Fogg C, de Lusignan S, Fraser SDS, Roderick P, Harris S, Barkham A, Patel HP, Clegg A. Using routine health care data to develop and validate a system dynamics simulation model of frailty trajectories in an ageing population. Health Systems 2025;1-13.

Jordão M, Gong L, Andre D, Akhtar A, Nwofe E, Hawkins R, Best K, Parveen S, Windle K, Clegg A. Minoritised ethnic groups and modifiable dementia risk: a scoping review of UK-based evidence, Epidemiol Community Health 2025. http://dx.doi.org/10.1136/jech-2024-222654

Taylor E, Goodwin V, Clegg A, Brown L, Frost J, Ball S. Predictors of independence in older people: A longitudinal, population-based study using the CARE75 + cohort. BMC Geriatrics 2025; 25:288. https://doi.org/10.1186/s12877-025-05927-4

Best K, Shuweihdi F, Alvarez JCB, Relton S, Avgerinou C, Nimmons D, Petersen I, Pujades-Rodriguez M, Conroy SP, Walters K, West RM, Clegg A, Development and external validation of the electronic frailty index 2 using routine primary care electronic health record data, Age and Ageing 2025; 54(4):afaf077. https://doi.org/10.1093/ageing/afaf077

Walters K, Frost R, Avgerinou C, Kalwarowsky S, Goodman C, Clegg A, Marston L, Pan S, Hopkins J, Jowett C, Elaswarapu R, Gardner B, Mahmood F, Prescott M, Thornton G, Skelton D, Gould R, Cooper C, Drennan V, Kharicha K, Logan P, Hunter R. Clinical and cost-effectiveness of a home-based health promotion intervention for older people with mild frailty in England: a multicentre, parallel-group, randomised controlled trial. The Lancet Healthy Longevity 2025;100670. https://doi.org/10.1016/j.lanhl.2024.100670

Almatrafi A, Gabe R, Beeken RJ, Neal RD, Clegg A, Best KE, Relton S, Brown M, Zhen Tam H, Hancock N, Crosbie PAJ, Callister MEJ. Impact of frailty and comorbidity on initial response to lung cancer screening invitation and low-dose CT screening uptake: Findings from the Yorkshire Lung Screening Trial. Journal of Medical Screening 2025. https://doi.org/10.1177/09691413251315087

Heaven A, Foster M, Foy R, Hawkins R, Hulme C, Humphrey S, Smith J, Clegg AP. Personalised care planning for older people with frailty: a review of factors influencing implementation. BJGP Open 2025. http://doi.org/10.3399/bjgpo.2024.0163

Carbery I, Todd O, Hale M, Black CJ, Clegg A, Selinger CP. Meta-Analysis: Prevalence of Frailty and Associated Adverse Events in Inflammatory Bowel Diseases. Alimentary Pharmacology and Theraputics 2024. https://doi.org/10.1111/apt.18390

Sun Y, Witham MD, Clegg A, Taylor RS, Dibben G, McAllister D, Hanlon P. A scoping review of the measurement and analysis of frailty in randomised controlled trials, Age and Ageing 2024;(5)3:11.afae258. https://doi.org/10.1093/ageing/afae258

Hancox Z, Pang A, Conaghan PG, Kingsbury SR, Clegg A, Relton SD. A systematic review of networks for prognostic prediction of health outcomes and diagnostic prediction of health conditions within Electronic Health Records. Artificial Intelligence in Medicine 2024;158. https://doi.org/10.1016/j.artmed.2024.102999

Walsh B, Fogg C, England T, Brailsford S, Roderick P, Harris S, Fraser S, Clegg A, de Lusignan s, Zhu m Lambert F, Barkham A, Harnish P, Widle V. Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning. Health and Social Care Delivery Research 2024;12(44). https://doi.org/10.3310/LKJF3976

Maharani A, Sinclair DR, Clegg A, Hanratty B, Nazroo J, Tampubolon G, Todd C, Witteenberg, O’Beukk TWm, Matthews FE. The association between frailty, care receipt and unmet need for care with the risk of hospital admissions. PLoS ONE 2024. https://doi.org/10.1371/journal.pone.0306858

Stolz E, Schultz A, Mayerl H, Roller-Wirnsberger R, Clegg A. Revisiting unstable disability and the fluctuations of frailty: a measurement burst approach. Age and Ageing 2024. 53(8):afae170. https://doi.org/10.1093/ageing/afae170

Elhusseina L, Robinson DE, Delmestri A, Clegg A, Prieto-Alhambra A, Silman A, Strauss V. Longitudinal trajectories of frailty are associated with short-term mortality in older people: a joint latent class models analysis using 2 UK primary care databases. Journal of Clinical Epidemiology 2024; 173:111442. https://doi.org/10.1016/j.jclinepi.2024.111442

Woodall AA, Abuzour AS, Wilson SA, Mair FS, Buchan I, Sheard SB, Atkinson P, Joyce DW, Symon P, Walker LE. Management of antipsychotics in primary care: Insights from healthcare professionals and policy makers in the United Kingdom PLoS ONE 2024. https://doi.org/10.1371/journal.pone.0294974

Abuzour A, Wilson SA, Woodall AA, Mair FS, Clegg A, Shantsila E, Gabbay M, Abaho M, Aslam A, Bollegala D, Cant H, Griffiths A, Hama L, Leeming G, Lo E, Maskell S, O’Connell M, Popoola O, Relton S, Ruddle RA, Schofield P, Sperrin M, Van Staa T, Buchan I, Walker LE. A qualitative exploration of barriers to efficient and effective structured medication reviews in primary care: Findings from the DynAIRx study. PLOS ONE 2024. https://doi.org/10.1371/journal.pone.0299770

Nadarajah R, Ludman P, Laroche C, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Clegg A, Gale CP. Presentation, care, coronary intervention and outcomes of patients with NSTEMI according to age: insights from the international prospective ACVC-EAPCI EORP NSTEMI registry. Age and Ageing 2024;53(8): afae179. https://doi.org/10.1093/ageing/afae179

Crocker TC, Lam N, Ensor J, Jordão M, Bajpai R, Bond M, Forster A, Riley R, Andre D, Brundle C, Ellwood A, Green J, Hale M, Morgan J, Patetsini E, Prescott M, Ramiz R, Todd O, Walford R, Gladman J and Clegg A. Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis. Health Technology Assessment 2024;28(48):1-194. https://doi.org/10.3310/HNRP2514

Avgerinou C, Walters K, Bazo-Alvarez JC, Osborn D, West R, Clegg AP, Petersen I. 2024. Severe Mental Illness as a risk factor for recorded diagnosis of osteoporosis and fragility fractures in people aged 50 and above: retrospective cohort study using UK primary care data. British Journal of General Practice 2024. https://doi.org/10.3399/BJGP.2024.0055

Bowler C, Moriarty E, Chawner M, Clegg A, De Biase S, Offord N, Romano V, Sayer AA, Smith A, Todd O, Witham MD. 2024. Nutritional Screening, Initial Management and Referral for Older People with Sarcopenia or Frailty – Results from a UK-Wide Survey. Journal of Frailty Sarcopenia and Falls 2024. http://dx.doi.org/10.22540/jfsf-09-131

Fogg C, England T, Zhu S, Jones J, de Lusignan S, Fraser SDS, Roderick P, Clegg A, Harris S, Brailsford S, Barkham A, Patel HP, Walsh B. 2024. Primary and secondary care service use and costs associated with frailty in an ageing population: longitudinal analysis of an English primary care cohort of adults aged 50 and over, 2006–2017. Age and Ageing 2024;53(2):afae010. http://dx.doi.org/10.1093/ageing/afae010

Crocker TF, Jordão M, Lam N, Ramiz R, Mirza L, Patel I, Ellwood A, Patetsini E, Ensor J, Forster A, Clegg A, Gladman J. Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials. Age and Ageing 2024;53:afae102. https://doi.org/10.1093/ageing/afae102

Taylor E, Frost J, Ball S, Clegg A, Brown L, Goodwin VA. Participation, autonomy and control are shared concepts within older people’s interpretations of independence: a qualitative interview study. Ageing and Society 2024:1-24. https://doi.org/10.1017/S0144686X23000740

Archer L, Relton S, Akbari A, Best K, Bucknall M, Conroy S, Hattle M, Hollinghurst J, Humphrey S, Lyons R, Richards S, Walters K, West R, van der Windt D, Riley R, Clegg A. Development and external validation of the eFalls tool: a multivariable prediction model for the risk of ED attendance or hospitalisation with a fall or fracture in older adults. Age and Ageing 2024;52(3). https://doi.org/10.1093/ageing/afae057

Crocker TF, Ensor J, Lam N, Jordão M, Bajpai R, Bond M, Forster A, Riley R, Andre D, Brundle C, Ellwood A, Green J, Hale M, Mirza L, Morgan J, Patel I, Patetsini E, Prescott M, Ramiz R, Todd O, Walford R, Gladman J, Clegg A. Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis. BMJ 2024384:e077764. https://doi.org/10.1136/bmj-2023-077764

Graham L, Brundle C, Harrison N, Andre D, Clegg A, Forster A, Spilsbury K. What are the priorities for research of older people living in their own home, including those living with frailty? A systematic review and content analysis of studies reporting older people’s priorities and unmet needs, Age and Ageing 2024; 53(1):afad232. https://doi.org/10.1093/ageing/afad232

Heaven A, Bower P, Day F, Farrin A, Fernadez C, Foster M, Foy R, Hawkins R, Hulme C, Humphrey S, Lawton R, Parker C, Thompson E, West R, Clegg A. PeRsOnaliSed care Planning for oldER people with frailty (PROSPER): protocol for a randomised controlled trial. Trials 2024;25,8. https://doi.org/10.1186/s13063-023-07857-1

Best K, Todd O, Clegg A. Are frailty measurements derived using electronic health records fit for clinical use? Age and Ageing 2024;53(2):afae001. https://academic.oup.com/ageing/article/53/2/afae001/7595905

Mahmoud A, Goodwin VA, Morley N, Whitney J, Lamb SE, Lyndon H, Creanor S, Frost J. How can we improve Comprehensive Geriatric Assessment for older people living with frailty in primary care and community settings? A qualitative study. BMJ Open 2024;14:e081304. http://dx.doi.org/10.1136/bmjopen-2023-081304

Gilbody S, Littlewood E, McMillan D, Atha L, Bailey D, Baird K, Brady S, Burke L, Chew-Graham CA, Coventry P, Crosland S, Fairhurst C, Henry A, Hollingsworth K, Newbronner E, Ryde E, Shearsmith L, Wang H-I, Webster J, Woodhouse R, Clegg A, Dexter-Smith S, Gentry T, Hewitt C, Hill A, Lovell K, Sloan C, Traviss-Turner G, Pratt S, Ekers D. Behavioural activation to mitigate the psychological impacts of COVID-19 restrictions on older people in England and Wales (BASIL+): a pragmatic randomised controlled trial. The Lancet Healthy Longevity 2024;5(2):e97-e107. http://dx.doi.org/10.1016/s2666-7568(23)00238-6

Taylor E, Goodwin V, Ball S, Clegg A, Brown L, Frost J. Older Adults’ Perspectives of Independence Through Time: Results of a Longitudinal Interview Study. The Gerontologist 2024;64(2):gnad073. https://doi.org/10.1093/geront/gnad073

Shiwani T, Relton S, Evans R, Kale A, Heaven A, Clegg A. Ageing Data Research Collaborative (Geridata) AI group, Todd O. New Horizons in artificial intelligence in the healthcare of older people, Age and Ageing 2023, 52(12): afad219. https://doi.org/10.1093/ageing/afad219

Welch C, Wilson D, Sayer AA, Miles D, Jackson WTA on behalf of the UK Geriatric Medicine Core Dataset Extended Working Group. (including Clegg A). Development of a UK core dataset for geriatric medicine research: a position statement and results from a Delphi consensus process. BMC Geriatrics 2023 23, 168. https://doi.org/10.1186/s12877-023-03805-5

Lam N, Green J, Hallas S, Forster A, Crocker TF, Andre D, Ellwood A, Clegg A, Brown L, on behalf of the POPPY Programme Group. Mapping review of pain management programmes and psychological therapies for community-dwelling older people living with pain. European Geriatric Medicine 2023; https://doi.org/10.1007/s41999-023-00871-1

Braithwaite E, Todd OM, Atkin A, Hulatt R, Tadrous R, Alldred D, Pirmohamed M, Walker L, Lawton R, Clegg A. Interventions for reducing anticholinergic medication burden in older adults – a systematic review and meta-analysis. Age and Ageing 2023 52(9) 176. https://doi.org/10.1093/ageing/afad176

Crocker TF, Lam N, Jordão M, Brundle C, Prescott M, Forster A, Ensor J, Gladman J, Clegg A. Risk-of-bias assessment using Cochrane’s revised tool for randomized trials (RoB 2) was useful but challenging and resource-intensive: observations from a systematic review. Journal of Clinical Epidemiology 2023;161:39-45. https://doi.org/10.1016/j.jclinepi.2023.06.015

Cheong VL, Mehdizadeh D, Todd OM, Gardner P, Zaman H, Clegg A, Alldred DP, Faisal M. The extent of anticholinergic burden across an older Welsh population living with frailty: cross-sectional analysis of general practice records. Age and Ageing 2023;52(7):afad136. https://doi.org/10.1093/ageing/afad136

Brown L, Mossabir R, Harrison N, Lam N, Grice A, Clegg A, Williams A, Antcliff D, Schofield P, Suleman A, Forster A. Developing the evidence and associated service models to support older adults living with frailty to manage their pain and to reduce its impact on their lives: protocol for a mixed-method, co-design study (The POPPY Study). BMJ Open 2023;13:e074785. http://dx.doi.org/10.1136/bmjopen-2023-074785

Todd O, Johnson O, Wilkinson C, Hollinghurst J, Dondo TB, Yadegarfar ME, Sheppard JP, McManus RJ, Gale CP, Clegg A. Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study. Age and Ageing 2023;52(5). afad077. https://doi.org/10.1093/ageing/afad077

Walsh B, Fogg C, Harris S, Roderick P, Lusignan SD, England T, Clegg A, Brailsford S, Fraser SDS. Frailty transitions and prevalence in an ageing population: longitudinal analysis of primary care data from an open cohort of adults aged 50 and over in England, 2006–2017. Age and Ageing 2023;52(5)afad058. https://doi.org/10.1093/ageing/afad058

Sheppard JP, Koshiaris C, Stevens R, Lay-Flurrie S, Banerjee A, Bellows BK, Clegg A, Hobbs FDR, Payne RA, Swain S, Usher-Smith JA, McManus RJ. The association between antihypertensive treatment and serious adverse events by age and frailty: A cohort study. PLoS Medicine 2023;20(4):e1004223. https://doi.org/10.1371/journal.pmed.1004223

Maharani A, Sinclair DR, Chandola T, Bower P, Clegg A, Hanratty B, Nazroo J, Pendleton N, Tampubolon G, Todd C, Wittenberg R, O’Neill TW, Matthews FE. Household wealth, neighbourhood deprivation and frailty amongst middle-aged and older adults in England: a longitudinal analysis over 15 years (2002–2017), Age and Ageing 2023;52(3): afad034. https://doi.org/10.1093/ageing/afad034

Avgerinou C, Petersen I, Clegg A, West RM, Osborn D, Walters K. Trends in incidence of recorded diagnosis of osteoporosis, osteopenia, and fragility fractures in people aged 50 years and above: retrospective cohort study using UK primary care data. Osteoporosis International 2023; https://doi.org/10.1007/s00198-023-06739-1

Koshiaris C, Archer L, Flurrie SL, Snell KIE, Riley RD, Stevens R, Banerjee A, Usher-Smith JA, Clegg A, Payne RA, Ogden M, Hobbs FDR, McManus RK, Sheppard JP. Predicting the risk of acute kidney injury in primary care: derivation and validation of STRATIFY-AKI. British Journal of General Practice 2023; BJGP.2022.0389. https://doi.org/10.3399/BJGP.2022.0389

Kaskirbayeva D, West R, Jaafari H, King N, Howdon D, Shuweihdi F, Clegg A, Nikolova S. Progression of frailty as measured by a cumulative deficit index: A systematic review. Ageing Research Reviews 2023;84:101789. https://doi.org/10.1016/j.arr.2022.101789

Walker LE, Abuzour AS, Bollegala D, Clegg A, Gabbay M, Griffiths A, Kullu C, Leeming G, Mair FS, Maskell S, Relton S, Ruddle RA, Shantsila E, Sperrin M, Van Staa T, Woodall A, Buchan I. The DynAIRx Project Protocol: Artificial Intelligence for dynamic prescribing optimisation and care integration in multimorbidity. Journal of Multimorbidity and Comorbidity 2022;12. https://doi.org/10.1177/26335565221145493

Ahmed S, Airlie J, Clegg A, Copsey B, Cundill B, Forster A, Heaven A, Johansson JF, Kime N, Moreau L, Ozer S, Parker C, Richards SH, Thompson E, Farrin AJ. A new opportunity for enhancing trial efficiency: Can we investigate intervention implementation processes within trials using SWAT (study within a trial) methodology? Research Methods in Medicine & Health Sciences 2022;3(3):66-73. https://doi.org/10.1177/26320843221080734

Rennie KJ, Witham M, Bradley P, Clegg A, Connolly S, Hancock HC, Hiu S, Marsay L, McDonald C, Robertson L, Simms L, Steel AJ, Steves CJ, Storey B, Wason J, Wilson N, von Zglinicki T, Sayer AAP. MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial. BMJ Open 2022;12(7):e061823. https://doi.org/10.1136%2Fbmjopen-2022-061823

Frost R, Avgerinou C, Goodman C, Clegg A, Hopkins J, Gould RL, Gardner B, Marston L, Hunter R, Manthorpe J, Cooper C, Skelton DA, Drennan VM, Logan P, Walters K. Clinical and cost-effectiveness of a personalised health promotion intervention enabling independence in older people with mild frailty (‘HomeHealth’) compared to treatment as usual: study protocol for a randomised controlled trial. BMC Geriatrics 2022;22:485 https://doi.org/10.1186/s12877-022-03160-x

Brundle C, Heaven A, Clegg A. Eligibility screening older research participants using remote cognitive assessment—experiences and reflections from a primary care randomised controlled trial. Trials 2022; 23:862. https://doi.org/10.1186/s13063-022-06805-9

Smith H, Grindey C, Hague I, Newbould L, Brown L, Clegg A, Thompson C, Lawton R. Reducing delayed transfer of care in older people: A qualitative study of barriers and facilitators to shorter hospital stays. Health Expectations 2022;1–17 https://doi.org/10.1111/hex.13588

Kime N, Wright A, Heaven A, Hawkins R, Smith J, Cundill B, Foy R, Lawton R, Farrin A, Hulme C, Clegg A. Implementing personalised care planning for older people with frailty: a process evaluation of the PROSPER feasibility trial. BMC Geriatrics 2022; 22(760). https://doi.org/10.1186/s12877-022-03426-4

Wilkinson C, Wu J, Clegg A, Nadarajah R, Rockwood K, Todd O, Gale CP. Impact of oral anticoagulation on the association between frailty and clinical outcomes in people with atrial fibrillation: Nationwide primary care records on treatment analysis. EP Europace 2022;24(7)1065–1075 https://doi.org/10.1093/europace/euac022

Clegg A, Bandeen-Roche K, Farrin A, Forster A, Gill TM, Gladman J, Kerse N, Lindley R, McManus RJ, Melis R, Mujica-Mota R, Raina P, Rockwood K, Teh R, van der Windt D, Witham M. New horizons in evidence-based care for older people: individual participant data meta-analysis. Age and Ageing 2022; 51(4):afac090 https://doi.org/10.1093/ageing/afac090

Fogg C, Fraser SDS, Roderick P, de Lusignan S, Clegg A, Brailsford S, Barkham A, Patel HP, Windle V, Harris S, Zhu S, England T, Evenden D, Lambert F, Walsh B & The Frailty Dynamics study team. The dynamics of frailty development and progression in older adults in primary care in England (2006–2017): a retrospective cohort profile. BMC Geriatrics 2022;22(30). https://doi.org/10.1186/s12877-021-02684-y

Jones D, Di Martino E, Bradley SH, Essang B, Hemphill S, Wright JM, Renzi C, Surr C, Clegg A, De Wit N, Neal R. Factors affecting the decision to investigate older adults with potential cancer symptoms: a systematic review. British Journal of General Practice 2021;72(714):e1-e10. https://doi.org/10.3399/bjgp.2021.0257

Hollinghurst J, Daniels H, Fry R, Akbari A, Rodgers S, Watkins A, Hillcoat-Nallétamby S, Williams N, Nikolova S, Meads D, Clegg A. Do home adaptation interventions help to reduce emergency fall admissions? A national longitudinal data-linkage study of 657,536 older adults living in Wales (UK) between 2010 and 2017. Age and Ageing 2022; 51(1):afab201, https://doi.org/10.1093/ageing/afab201

Todd OM, Clegg A. Prognostic tools for the care of older adults presenting with trauma. Age and Ageing 2021. afab249, https://doi.org/10.1093/ageing/afab249

Gilbody S, Littlewood E, McMillan D, Chew-Graham CA, Bailey D, Gascoyne S, Sloan C, Burke L, Coventry P, Crosland S, Fairhurst C, Henry A, Hewitt C, Joshi K, Ryde E, Shearsmith L, Traviss-Turner G, Woodhouse R, Clegg A, Gentry T, Hill AJ, Lovell K, Dexter Smith S, Webster J, Ekers D. Behavioural activation to prevent depression and loneliness among socially isolated older people with long-term conditions: The BASIL COVID-19 pilot randomised controlled trial. PLoS Medicine 2021;18(10):e1003779. https://doi.org/10.1371/journal.pmed.1003779

Jones D, Di Martino E, Bradley SH, Essang B, Hemphill S, Wright JM, Renzi C, Surr C, Clegg A, De Wit N, Neal R. Factors affecting the decision to investigate older adults with potential cancer symptoms: a systematic review. British Journal of General Practice 2021;BJGP.2021.0257. https://doi.org/10.3399/bjgp.2021.0257

Hollinghurst J, Daniels H, Fry R, Akbari A, Rodgers S, Watkins A, Hillcoat-Nallétamby S, Williams N, Nikolova S, Meads D, Clegg A. Do home adaptation interventions help to reduce emergency fall admissions? A national longitudinal data-linkage study of 657,536 older adults living in Wales (UK) between 2010 and 2017, Age and Ageing 2021; afab201, https://doi.org/10.1093/ageing/afab201

Brown L, Heaven A, Quinn C, Goodwin V, Chew-Graham C, Mahmood F, Hallas S, Jacob I, Brundle C, Best K, Daffu-O’Reilly A, Spilsbury K, Young TA, Hawkins R, Hanratty B, Teale E, Clegg A. Community Ageing Research 75+ (CARE75+) REMOTE study: a remote model of recruitment and assessment of the health, well-being and social circumstances of older people. BMJ Open 2021;11(11):e048524. https://doi.org/10.1136/bmjopen-2020-048524

Prescott M, Lilley-Kelly A. Cundill B, Clarke D, Drake S, Farrin AJ, Forster A, Goodwin M, Goodwin VA, Hall AJ, Hartley S, Holland M, Hulme C, Nikolova S, Parker C, Wright P, Ziegler F, Clegg A. Home-based Extended Rehabilitation for Older people (HERO): study protocol for an individually randomised controlled multi-centre trial to determine the clinical and cost-effectiveness of a home-based exercise intervention for older people with frailty as extended rehabilitation following acute illness or injury including embedded process evaluation. Trials 2021;22(783). https://doi.org/10.1186/s13063-021-05778-5.

Nikolova S, Heaven A, Hulme C, West R, Pendleton N, Humphrey S, Cundill B, Clegg A. Social care costs for community-dwelling older people living with frailty Health and Social Care in the Community 2021; https://doi.org/10.1111/hsc.13450

Wilkinson C, Clegg A, Todd O, Rockwood K, Yadegarfar ME, Gale CP, Hall M. Atrial fibrillation and oral anticoagulation in older people with frailty: a nationwide primary care electronic health records cohort study. Age Ageing 2021; 50(3):772-779

Chawner M, De Biase S, Offord NJ, Todd O, Clegg A, Sayer AA, Witham MD. Do Exercise Programmes For Older People With Sarcopenia Or Frailty Deliver An Evidence-Based Service? Findings From A UK Survey. Age Ageing 2021;50(1): i12–i42.

Harrison N, Brundle C, Heaven A, Clegg A. The cost of community research—recruiting community-dwelling participants to a feasibility primary care cluster randomised controlled trial. Trials 2021;22:332. https://doi.org/10.1186/s13063-021-05297-3

Witham MD, Heslop P, Dodds RM, Clegg AP, Hope SV, McDonald C, Smithard D, Storey B, Tan AL, Thornhill A, Sayer AA. Developing a UK sarcopenia registry: recruitment and baseline characteristics of the SarcNet pilot. Age and Ageing 2021 afab084, https://doi.org/10.1093/ageing/afab084

Hinde S, Bojke L, Richardson G, Birks Y, Whittaker W, Wilberforce M, Clegg A. Delayed transfers of care for older people: a wider perspective. Age Ageing 2021. afab035, https://doi.org/10.1093/ageing/afab035

Crocker TF, Clegg A, Riley RD, Lam N, Bajpai R, Jordão M, Patetsini E, Ramiz R, Ensor J, Forster A, Gladman JRF. Community-based complex interventions to sustain independence in older people, stratified by frailty: a protocol for a systematic review and network meta-analysis. BMJ Open 2021;11(2):e045637. https://doi.org/10.1136/bmjopen-2020-045637

Farrow M, Biglands J, Tanner SF, Clegg A, Brown L, Hensor EMA, O’Connor P, Emery P, Tan AL. The effect of ageing on skeletal muscle as assessed by quantitative MR imaging: an association with frailty and muscle strength. Aging Clinical and Experimental Research 2021. 33:291–301 https://doi.org/10.1007/s40520-020-01530-2

Jacob I, Mahmood F, Brown L, Heaven A, Mahmood S, Clegg A. Recruiting older people from the Pakistani community in Community Ageing Research 75+. British Journal of Community Nursing 2020;25(3):110–113/ https://doi.org/10.12968/bjcn.2020.25.3.110

Witham MD, Chawner M, Biase S, et al. Content of exercise programmes targeting older people with sarcopenia or frailty – findings from a UK survey. Journal of frailty, sarcopenia and falls 2020;5(1):17-23. https://dx.doi.org/10.22540%2FJFSF-05-017

Coventry PA, McMillan D, Clegg, A, Brown L, van der Feltz-Cornelis C, Gilbody S, Ali S. Frailty and depression predict instrumental activities of daily living in older adults: A population-based longitudinal study using the CARE75+ cohort. PLOS one, 2020;15(12), p.e0243972.

Hollinghurst J, Housley G, Watkins A, Clegg A, Gilbert T Conroy SP. A comparison of two national frailty scoring systems. Age Ageing 2020, afaa252, https://doi.org/10.1093/ageing/afaa252

Ahmed S, Heaven A, Lawton R, Rawlings G, Sloan C, Clegg A. Behaviour change techniques in personalised care planning for older people: systematic review. British Journal of General Practice 2020; bjgp20X714017. https://doi.org/10.3399/bjgp20X714017

Wilkinson C, Wu J, Searle SD, Todd O, Hall M, Kunadian V, Clegg A, Rockwood K, Gale CP. Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial. BMC Medicine 2020; 18:401. https://doi.org/10.1186/s12916-020-01870-w

O’Caoimh R, Sezgin D, O’Donovan MR, Molloy DW, Clegg A, Rockwood K, Liew A. Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies. Age Ageing 2020, afaa219, https://doi.org/10.1093/ageing/afaa219

Munyombwe T, West RM, Pendleton N, Clegg A. Mapping between the Electronic Frailty Index and a Research Standard Frailty Index: Findings from the Community Ageing Research 75+ (CARE 75+) Cohort Study. Advances in Geriatric Medicine and Research 2020;2(4):e200023. https://doi.org/10.20900/agmr20200023

Brown L, Mossabir R, Harrison N, Brundle C, Smith J, Clegg A. Life in lockdown: A telephone survey to investigate the impact of COVID-19 lockdown measures on the lives of older people (≥ 75years). Age Ageing 2020; afaa255, https://doi.org/10.1093/ageing/afaa255

Muscedere J, Afilalo J, de Carvalho IA, Cesari M, Clegg A, Eriksen HE, Evans KR, Heckman G, Hirdes JP, Kim PM, Laffon B, Lynn J, Martin F, Prorok JC, Rockwood K, Manas LR, Rolfson D, Shaw G, Shea B, Sinha S, Theou O, Tugwell P, Valdiglesias V, Vellas B, Veronese N, Wallace LMK, Williamson PR & the Canadian Frailty Network. Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research. Journal of Frailty & Aging 2020;9(1)14-22. http://doi.org/10.14283/jfa.2019.43

Hale M, Zaman H, Mehdizadeh D, Todd O, Callaghan H, Gale CP, Clegg A. Association between Statins Prescribed for Primary and Secondary Prevention and Major Adverse Cardiac Events among Older Adults with Frailty: A Systematic Review. Drugs & Aging 2020; 37:787–799 https://doi.org/10.1007/s40266-020-00798-3

Nikolova S, Hulme C, West R, Pendleton N, Heaven A, Bower P, Humphrey S, Farrin A, Cundill B, Hawkins R, Clegg A. Normative Estimates and Agreement Between 2 Measures of Health-Related Quality of Life in Older People With Frailty: Findings From the Community Ageing Research 75+ Cohort. Patient-Reported Outcomes 2020:23(8)1056-1062. https://doi.org/10.1016/j.jval.2020.04.1830

Heaven A, Bower B, Cundill B, Farrin A, Foster M, Foy R, Hartley S, Hawkins R, Hulme C, Humphrey S, Lawton R, Parker C, Pendleton N, West R, Young J, Clegg A. Study protocol for a cluster randomised controlled feasibility trial evaluating personalised care planning for older people with frailty: PROSPER V2 27/11/18. Pilot and Feasibility Studies 2020; 6:56. doi.org/10.1186/s40814-020-00598-x

Sezgin D, O’Donovan M, Wong J W, Bandeen-Roche K, Liotta G, Fairhall N, Laso AR, Apóstolo J, Clarnette R, Holland C, Roller-Wirnsberger R, Illario M, Mañas MR, Vollenbroek-Hutten M, Yavuz BB, Balci C, Pernas FO, Paul C, Ahern E, Romero-Ortuno R, Molloy W, Cooney MT, O’Shea D, Cooke J, Lang D, Hendry A, Rockwood K, Clegg A, Liew A, O’Caoimh R. 269 Early Identification of Frailty: Developing an International Delphi Consensus for a Definition of Pre-frailty, Age and Ageing 2019;48(3):iii17–iii65, https://doi.org/10.1093/ageing/afz103.168

Jacob I, Mahmood F, Brown L, Heaven A, Mahmood S, Clegg A. Recruiting older people from the Pakistani community in Community Ageing Research 75+. British Journal of Community Nursing 2020;25(3):110–113 doi: 10.12968/bjcn.2020.25.3.110

Todd OM, Burton JK, Dodds RM, Hollinghurst J, Lyons RA, Quinn TJ, Schneider A, Walesby KE, Wilkinson C, Conroy S, Gale CP, Hall M, Walters K, Clegg AP. New Horizons in the use of routine data for ageing research. Age Ageing, 2020; afaa018, https://doi.org/10.1093/ageing/afaa018

Hale MD, Santorelli G, Brundle C, Clegg A. A cross-sectional study assessing agreement between self-reported and general practice recorded health conditions among community dwelling older adults. Age Ageing 2019;49(1):135-140. doi: 10.1093/ageing/afz124

Todd OM, Wilkinson C, Hale M, Wong NL, Hall M, Sheppard JP, McManus RJ, Rockwood K, Young J, Gale CP, Clegg A. Is the association between blood pressure and mortality in older adults different with frailty? A systematic review and meta-analysis. Age Ageing 2019;48(5):627-635. doi: 10.1093/ageing/afz072.

Hale M, Shah S, Clegg A. Frailty, inequality and resilience. Clinical Medicine 2019;19(3):219-223. doi: 10.7861/clinmedicine.19-3-219.

Offord NJ, Clegg A, Turner G, Dodds RM, Sayer AA, Witham MD. Current practice in the diagnosis and management of sarcopenia and frailty – results from a UK-wide survey Journal of Frailty Sarcopenia & Falls 2019 J Frailty Sarcopenia Falls. 2019;4(3):71-77. doi: 10.22540/JFSF-04-071.

Witham MD, Roberts HC, Gladman J, Stott DJ, Aihie Sayer A, Aspray TJ, Brock P, Clegg A, Cox N, Ewan V, Frith J, Burton JK, Jackson T, Lewis EG, Lim SE, Makin S, Lochlainn MN, Richardson S, Shenkin SD, Steves CJ, Todd O, Tullo E, Walker R, Yarnall A. Extended Working Group* from the NIHR Newcastle Biomedical Research Centre Meeting. Growing research in geriatric medicine. Age Ageing. 2019 [online] doi: 10.1093/ageing/afy220

Brown L, Young J, Teale E, Santorelli G, Clegg A. A Cross-Sectional Study of the Impact of Pain in Older People with Frailty: Findings from the Community Ageing Research 75+ (CARE75+) Study. Advances in Geriatric Medicine and Research 2019;1:e190002. https://doi.org/10.20900/agmr20190002

Heaven A, Brown L, Young J, Teale E, Hawkins R, Spilsbury K, Mountain G, Young T, Goodwin V, Hanratty B, Chew-Graham C, Brundle C, Mahmood F, Jacob I, Daffu-O’Reilly A, Clegg A. Community ageing research 75+ study (CARE75+): an experimental ageing and frailty research cohort. BMJ Open 2019;9(3):e026744. doi: 10.1136/bmjopen-2018-026744

Crocker TF, Brown L, Clegg A, Farley K, Franklin M, Simpkins S, Young J. Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis. Quality of life research 2019;28:2041–2056. https://doi.org/10.1007/s11136-019-02149-1

Brundle C, Heaven A, Brown L, Teale E, Young J, West R, Clegg A. Convergent validity of the electronic frailty index. Age Ageing 2019;48(1):152-156.

Wilkinson C, Todd O, Clegg A, Gale CP, Hall M. Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis. Age Ageing 2018 doi: 10.1093/ageing/afy180. [Epub ahead of print]

Reeves D, Pye S, Ashcroft D, Clegg A, Kontopantelis E, Blakeman T, VanMarwijk H. The challenge of ageing populations and frail people: can primary care adapt? BMJ 28;362:k3349. doi: 10.1136/bmj.k3349.

Clegg A, Hassan-Smith Z. Frailty and the endocrine system. Lancet Diabetes and Endocrinology 2018;6(9):743-752. doi: 10.1016/S2213-8587(18)30110-4

Stow D. Hanratty B, Robinson L, Barclay SIG, Iliffe S, De-Biase S, Clegg A, Matthews F. Evaluating frailty scores to predict mortality in older adults using data from population based electronic health records: case control study. Age Ageing 2018. doi: 10.1093/ageing/afy022

Pugh R, Ellison A, Pye K, Subbe CP, Thorpe CM, Lone NI, Clegg A. Feasibility and reliability of frailty assessment in the critically ill: a systematic review. Critical Care 2018; 22:49. doi: 10.1186/s13054-018-1953-9.

Bebb O, Smith FGD, Clegg A, Hall M, Gale CP. Frailty and acute coronary syndrome: A structured literature review. European Heart Journal: Acute Cardiovascular Care 2017 (online). doi.org/10.1177/2048872617700873

Teale EA, Siddiqi N, Clegg A, Todd OM, Young J. Non-pharmacological interventions for managing delirium in hospitalised patients. 2016 Mar 11;3:CD005563. doi: 10.1002/14651858.CD005563.pub3.

Clegg A, Bates C, Young J, Ryan R, Nichols L, Teale EA, Mohammed MA, Parry J, Marshall T. Development and validation of an electronic frailty index using routine primary care electronic health record data. Age and ageing. 2017;5(3):353-60. doi: 10.1093/ageing/afw039.

Yarnall AJ, Sayer AA, Clegg A, Rockwood K, Parker S, Hindle JV. New horizons in multimorbidity in older adults. Age and Ageing. 2017;46(6):882-888.

Todd O, Clegg A. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. The New England journal of medicine. 2016;374:2290-2295.doi: 10.1056/NEJMc1602668

Heaven A. Brown L, Foster M; Clegg A. Keeping it credible in cohort multiple Randomised Controlled Trials: the Community Ageing Research 75+ (CARE 75+) study model of patient and public involvement and engagement Research Involvement and Engagement 2016doi: 10.1186/s40900-016-0044-9.

Clegg A, Bates C, Young J, Ryan R, Nichols L, Teale E, Mohammed MA, Parry J, Marshall T Development and validation of an electronic frailty index using routine primary care electronic health record data Age Ageing 2016;45(3):353-60.

Siddiqi N, Harrison JK, Clegg A, Teale EA, Young J, Taylor J, Simpkins SA. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database of Systematic Reviews 2016; DOI 10.1002/14651858.CD005563.pub3. Issue 3.

Clegg A, Young J. Frailty and organization of health and social care. In:Frailty in Aging: Biological, Clinical and Social Implications. Editors: O Theou, K Rockwood. Karger 2015;48:161-173.

Brown L, Young Y, Clegg A, Heaven A. Pain in older people with frailty. Reviews of Clinical Gerontology 2015;25(03): 159-171.

Harrison J, Clegg A, Conroy S, Young J. Managing frailty as a long-term condition. Age Ageing 2015;44:732–735.

Clegg A, Young J. Frailty and Organization of Health and Social Care. Interdisciplinary topics in gerontology and geriatrics 2015;41:161-173.

Siddiqi N, Clegg A, Simpkins SA, Young J, Holt R, Harrison JK, Taylor J. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database of Systematic Reviews 2015;1. Art. No.: CD005563. DOI: 10.1002/14651858. CD005563.pub2.

Clegg A,Rogers L, Young J.Diagnostic test accuracy of simple instruments for identifying frailty in community dwelling older people. Age Ageing 2015;44(1):148-152.

Clegg A,Relton C, Young J,Witham M. Improving recruitment of older people to clinical trials: use of the cohort multiple randomised controlled trial design. Age Ageing 2015;44(4):547-550.

Handforth C, Clegg A,Young C, Simpkins S, Seymour MT, Selby P, Young J.The prevalence and outcomes of frailty in older cancer patients: a systematic review. Annals of Oncology 2015; 26(6):1091-1101.

Heaven A,Cheater F, Clegg A, Collinson M, Farrin A, Forster A, Godfrey M,et al. Pilot trial of Stop Delirium! (PiTStop) – A complex intervention to prevent delirium in care homes for older people: study protocol for a cluster randomised controlled trial. Trials 2014;15:47.

Turner G, Clegg A.Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report. Age Ageing 2014;43(6):744-747.

Clegg A, Bates C, Young J, Teale E, Parry J. Development and validation of an electronic frailty index using existing primary care health record data. Age Ageing 2014;43(2):ii19. [Abstract].

Clegg A, Barber S, Young J, Iliffe S, Forster A. (HOPE) trial: a pilot randomised controlled trial of a home-based exercise intervention for older people with frailty. Age Ageing 2014;43(5):687-695.

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. The Lancet 2013; (9868): 752-62.

Clegg A, Young J, Siddiqi N. Delirium in cardiac patients: a clinical review. British Journal of Cardiac Nursing 2012; 7(3): 111-5.

Clegg A, Siddiqi N, Holt R, Young J. Interventions for preventing delirium in older people in institutional long-term care (protocol). Cochrane Database of Systematic Reviews 2012, Issue 1. Art. No.: CD009537. DOI: 10.1002/14651858.CD009357.

Clegg A, Barber S, Young J, Forster A, Iliffe S. Do home-based exercise interventions improve outcomes for frail older people? Findings from a systematic review. Reviews in Clinical Gerontology 2012 22;68-78.

Barber S, Clegg A, Young J. Is there a role for physical activity in preventing cognitive decline in people with mild cognitive impairment? Age Ageing 2012;41:5-8.

Clegg A, Young J. In-hospital delirium risk assessment, diagnosis and management: medications to avoid. Italian Journal of Medicine 2011;5:98-102.

Clegg A, Barber S, Young J, Forster A, Iliffe S. The Home-Based Older People’s Exercise (HOPE) trial: study protocol for a randomised controlled trial. BMC Trials 2011;12:143.

Clegg A, Young J. Which medications to avoid in people at risk of delirium: a systematic review. Age Ageing Jan 2011; 40(1):23-29.

Clegg A, Young J. The Frailty Syndrome. Clinical Medicine 2011;11(1):72-75.

Clegg A, Westby M, Young J. Under-reporting of delirium in the NHS. Age Ageing Mar 2011; 40(2):283-286.

Clegg A, Smith S. Gerotechnology series: bedding aids. European Geriatric Medicine. 2010; 1(6): 385-390.

Clegg A, Daverede L, Wong W, Loney E, Young J. Recurrent syncope and chronic ear pain. BMJ Case Reports 2010; 1-3.

Siddiqi N; Clegg A; Young J. Delirium in care homes. Reviews in Clinical Gerontology 2009; 19:309-316.

Clegg A, Young J. Frailty and organization of health and social care. In:Frailty in Aging: Biological, Clinical and Social Implications. Editors: O Theou, K Rockwood. Karger 2015;48:161-173.